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My Cart> Protein and Immunity > Blocking Peptides > ADAM17(Cleaved-Arg215) Antibody Blocking PeptideStorage：Store at -20℃，2 years.Avoid freeze/thaw cycles.
Appearance：Lyophilized powder
Gene ID：6868
Application：Blocking Peptide of K111494P Antibody
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| Name | ADAM17(Cleaved-Arg215) Antibody Blocking Peptide |
| Appearance | Lyophilized powder |
| Storage | Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| Swiss Prot | P78536 |
| Gene ID | 6868 |
| Interval Range | 200-250/824aa |
| Background | Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form (PubMed:9034191). Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface (PubMed:20592283). Responsible for the proteolytic release of several other cell-surface proteins， including p75 TNF-receptor， interleukin 1 receptor type II， p55 TNF-receptor， transforming growth factor-alpha， L-selectin， growth hormone receptor， MUC1 and the amyloid precursor protein (PubMed:12441351). Acts as an activator of Notch pathway by mediating cleavage of Notch， generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT) (PubMed:24226769). Plays a role in the proteolytic processing of ACE2 (PubMed:24227843). Plays a role in hemostasis through shedding of GP1BA， the platelet glycoprotein Ib alpha chain (By similarity). Mediates the proteolytic cleavage of LAG3， leading to release the secreted form of LAG3 (By similarity). Mediates the proteolytic cleavage of IL6R， leading to the release of secreted form of IL6R (PubMed:26876177， PubMed:28060820). |
| Application | Blocking Peptide of K111494P Antibody |
| Source | Synthetic |
| Purification Method | HPLC |
| Biological Activity | Not tested |
| Unit | Piece |
| Specification | 500ug |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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