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My CartStorage：Store at -20℃，2 years.Avoid freeze/thaw cycles.
Appearance：Lyophilized powder
Gene ID：57551
Application：Blocking Peptide of K111579P Antibody
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| Name | TAOK1 Antibody Blocking Peptide |
| Appearance | Lyophilized powder |
| Storage | Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| Swiss Prot | Q7L7X3 |
| Gene ID | 57551 |
| Interval Range | 415-465/1001aa |
| Background | Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade， DNA damage response and regulation of cytoskeleton stability. Phosphorylates MAP2K3， MAP2K6 and MARK2. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of the upstream MAP2K3 and MAP2K6 kinases. Involved in G-protein coupled receptor signaling to p38/MAPK14. In response to DNA damage， involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade， probably by mediating phosphorylation of MAP2K3 and MAP2K6. Acts as a regulator of cytoskeleton stability by phosphorylating ’Thr-208’ of MARK2， leading to activate MARK2 kinase activity and subsequent phosphorylation and detachment of MAPT/TAU from microtubules. Also acts as a regulator of apoptosis: regulates apoptotic morphological changes， including cell contraction， membrane blebbing and apoptotic bodies formation via activation of the MAPK8/JNK cascade. |
| Application | Blocking Peptide of K111579P Antibody |
| Source | Synthetic |
| Purification Method | HPLC |
| Biological Activity | Not tested |
| Unit | Piece |
| Specification | 500ug |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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