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My CartPurity：≥95% as determined by reducing SDS-PAGE.
Storage：Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Appearance：Lyophilized from a 0.2 μm filtered solution of 300mM NaAc, pH 6.5.
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| Appearance | Lyophilized from a 0.2 μm filtered solution of 300mM NaAc, pH 6.5. |
| Purity | ≥95% as determined by reducing SDS-PAGE. |
| Storage | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| Transport Condition | The product is shipped at ambient temperature. |
| Background | Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin.Mature IGFs are generated by proteolytic processing of inactive precursor proteins，which contains the N- and C-terminal propeptide regions.Mature human IGF-I consisting of 70 amino acids has 94% identity with mouse IGF-I and exhibits cross-species activity.IGF-1 binds IGF-IR，IGF-IIR，and the insulin receptor and plays a key role in cell cycle progression，cell proliferation and tumor progression.IGF-1 expression is regulated by growth hormone.R3 IGF-1 is an 83 amino acid analog of IGF-1 comprising the complete human IGF-1 sequence with the substitution of an Arg (R) for the Glu(E) at position three，hence R3，and a 13 amino acid extension peptide at the N terminus.R3 IGF-1 has been produced with the purpose of increasing biological activity.R3 IGF-1 is significantly more potent than human IGF-I in vitro. |
| Source | E.coli |
| Solvent | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Endotoxin | Less than 0.05 ng/ug(0.5 IEU/ug)as determined by LAL test. |
| Unit | Piece |
| Specification | 10ug 50ug 500ug 1mg |
Recombinant Human Insulin-like Growth Factor I is produced by our E.coli expression system and the target gene encoding Gly49-Ala118 is expressed.
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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IGF-1 Combined with OPN Promotes Neuronal Axon Growth in Vitro Through the IGF-1R/Akt/mTOR Signaling Pathway in Lipid Rafts
Click to check >>Author：Zhao Qin, Su Hong, Jiang Wei, Luo Haodong, Pan Lu, Liu Yuan, Yang Ce, Yin Ying, Yu Lehua, Tan Botao
IF：4.4000
Publish_to：NEUROCHEMICAL RESEARCH
PMID：37395917
