Gap 27
Cat.No:CLP1341 Solarbio
CAS:198284-64-9
Molecular Formula:C60H101N15O17
Molecular Weight:1304.53
Purity:≥95%
Appearance:Lyophilized powder
Storage:Store at -20℃,2 years.(Avoid freeze/thaw cycles)
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My CartCAS:198284-64-9
Molecular Formula:C60H101N15O17
Molecular Weight:1304.53
Purity:≥95%
Appearance:Lyophilized powder
Storage:Store at -20℃,2 years.(Avoid freeze/thaw cycles)
Qty:
Size:
Product Type | Peptides |
CAS | 198284-64-9 |
Sequence(1LC) | SRPTEKTIFII |
Sequence(3LC) | Ser-Arg-Pro-Thr-Glu-Lys-Thr-Ile-Phe-Ile-Ile |
Molecular Formula | C60H101N15O17 |
Molecular Weight | 1304.53 |
Purity | ≥95% |
Appearance | Lyophilized powder |
Solubility | DMSO:50 mg/mL; 0.1 M HCL:50 mg/mL; H2O:26.32 mg/mL (adjust pH to 3 with 0.1 M HCL); *Ultrasonic solubilization; |
Salt Form | Trifluoroacetate salt |
Source | Synthetic |
Storage | Store at -20℃,2 years.(Avoid freeze/thaw cycles) |
Category/Label | Substrate and Enzyme Inhibitors |
Background | Gap 27, a synthetic connexin43 mimetic peptide, is a gap junction inhibitor. Gap 27 possesses conserved sequence homology to a portion of the second extracellular loop leading into the fourth transmembrane connexin segment. |
Reference | [1]. Ilvesaro J, et al. Connexin-mimetic peptide Gap 27 decreases osteoclastic activity. BMC Musculoskelet Disord. 2001;2:10. [2]. Edwards G, et al. Role of gap junctions in the responses to EDHF in rat and guinea-pig small arteries. Br J Pharmacol. 1999 Dec;128(8):1788-94. [3]. Chaytor AT,e t al. Central role of heterocellular gap junctional communication in endothelium-dependent relaxations of rabbit arteries. J Physiol. 1998 Apr 15;508 ( Pt 2):561-73. |
Unit | Bottle |
Specification | 1mg 5mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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