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My CartCAS：1187852-48-7
Molecular Formula：C72H116N20O19
Molecular Weight：1565.81
Purity：≥95%
Appearance：Lyophilized powder
Storage：Store at -20℃，2 years.(Avoid freeze/thaw cycles)
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| Product Type | Peptides |
| CAS | 1187852-48-7 |
| Sequence(1LC) | KEFLHPSKVDLPR |
| Sequence(3LC) | Lys-Glu-Phe-Leu-His-Pro-Ser-Lys-Val-Asp-Leu-Pro-Arg |
| Molecular Formula | C72H116N20O19 |
| Molecular Weight | 1565.81 |
| Purity | ≥95% |
| Appearance | Lyophilized powder |
| Salt Form | Trifluoroacetate salt |
| Source | Synthetic |
| Storage | Store at -20℃，2 years.(Avoid freeze/thaw cycles) |
| Category/Label | Substrate and Enzyme Inhibitors |
| Background | SOR-C13， a carboxy-terminal truncated peptide， is a high-affinity TRPV6 antagonist with an IC50 value of 14 nM. TRPV6 is a non-voltage gated calcium channel that is associated with malignancy and poor prognosis in breast cancer. SOR-C13 has anticancer activity. |
| Reference | [1]. S Fu?， et al. Erratum to: First-in-human phase I study of SOR-C13， a TRPV6 calcium channel inhibitor， in patients with advanced solid tumors. Invest New Drugs. 2017 Jun;35(3):397.? [2]. Hui Xue， et al. Inhibition of Transient Receptor Potential Vanilloid 6 channel， elevated in human ovarian cancers， reduces tumour growth in a xenograft model. J Cancer. 2018 Aug 6;9(17):3196-3207. |
| Unit | Bottle |
| Specification | 1mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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