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My Cart> Cell Biology > Cell Detection > Cell Growth Factor > Recombinant Human IL-18/IL-1F4Purity：≥95% as determined by reducing SDS-PAGE.
Storage：Powder:＜-20℃ for long store;RT，3 weeks.Liquid:4-7℃，2-7 days;＜-20℃，3 months.
Appearance：Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
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| Appearance | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| Purity | ≥95% as determined by reducing SDS-PAGE. |
| Storage | Powder:＜-20℃ for long store;RT，3 weeks.Liquid:4-7℃，2-7 days;＜-20℃，3 months. |
| Transport Condition | The product is shipped at ambient temperature. |
| Background | Interleukin-18 is a secreted protein and it belongs to the IL-1 family.IL-18 is a proinflammatory cytokine and produced by macrophages and other cells.This cytokine can induce the IFN-gamma production of T cells.The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production，and enhance IgG2a production of B cells.IL-18 binding protein (IL18BP) can specifically interact with this cytokine，and thus negatively regulate its biological activity.After stimulation with IL-18，natural killer (NK) cells and certain T cells release another important cytokine called interferon-γ (IFN-γ) or type II interferon that plays an important role in activating the macrophages or other cells. |
| Source | Human cells |
| Solvent | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Endotoxin | Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test. |
| Unit | Piece |
| Specification | 10ug 50ug 500ug 1mg |
Recombinant Human Interleukin-18 is produced by our Mammalian expression system and the target gene encoding Tyr37-Asp193 is expressed with a 6His tag at the C-terminus.
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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