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My Cart> Cell Biology > Cell Detection > Cell Growth Factor > Recombinant Human CD28/TP44Purity：≥95% as determined by reducing SDS-PAGE.
Storage：Powder:＜-20℃ for long store;RT，3 weeks.Liquid:4-7℃，2-7 days;＜-20℃，3 months.
Appearance：Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
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| Appearance | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| Purity | ≥95% as determined by reducing SDS-PAGE. |
| Storage | Powder:＜-20℃ for long store;RT，3 weeks.Liquid:4-7℃，2-7 days;＜-20℃，3 months. |
| Transport Condition | The product is shipped at ambient temperature. |
| Background | T-cell-specific surface glycoprotein CD28(CD28) is a single-pass typeI membrane protein which contains one Ig-likeV-type (immunoglobulin-like) domain.It belongs to the immunoglobulin(Ig) superfamily.CD28 is one of the molecules expressed on T cells that provide co-stimulatory signals，which are required for T cell activation.CD28 co-stimulation is necessary for CD4 positive T-cell proliferation and survival，interleukin-2 production，and T-helper type-2 development.Human post-thymic regulatory T cells require CD28 co-stimulation to expand and maintain potent suppressive function in vivo.Apoptosis plays a key role in the age-related decline of CD28 expression and in immunosenescence.CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2).When activated by Toll-like receptor ligands，the CD80 expression is upregulated in antigen presenting cells (APCs).The CD86 expression on antigen presenting cells is constitutive.CD28 is the only B7 receptor constitutively expressed on naive T cells. |
| Source | Human cells |
| Solvent | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Endotoxin | Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test. |
| Unit | Piece |
| Specification | 10ug 50ug 500ug 1mg |
Recombinant Human T-cell-specific surface glycoprotein CD28 is produced by our Mammalian expression system and the target gene encoding Asn19-Pro152 is expressed with a Fc tag at the C-terminus.
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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