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My CartCAS：211439-12-2
Molecular Formula：C36H60N10O12
Molecular Weight：824.92
Purity：≥95%
Appearance：Lyophilized powder
Storage：Store at -20℃，2 years.(Avoid freeze/thaw cycles)
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| Product Type | Peptides |
| CAS | 211439-12-2 |
| Sequence(1LC) | NAPVSIPQ |
| Sequence(3LC) | Asn-Ala-Pro-Val-Ser-Ile-Pro-Gln |
| Molecular Formula | C36H60N10O12 |
| Molecular Weight | 824.92 |
| Purity | ≥95% |
| Appearance | Lyophilized powder |
| Solubility | DMSO：125 mg/mL; H2O：100 mg/mL; *Ultrasonic solubilization; |
| Salt Form | Trifluoroacetate salt |
| Source | Synthetic |
| Storage | Store at -20℃，2 years.(Avoid freeze/thaw cycles) |
| Category/Label | Amyloid Peptides |
| Background | Davunetide is an eight amino acid snippet derived from activity-dependent neuroprotective protein (ADNP)， a neurotrophic factor that exists in the mammalian CNS. Davunetide possesses neuroprotective， neurotrophic and cognitive protective roperties. Davunetide， a microtubule-stabilizing peptide， interacts with and stabilises neuron-specific βIII-tubulin in vitro. Davunetide penetrates the blood-brain barrier and is non-toxic. Davunetide inhibits Aβ aggregation and Aβ-induced neurotoxicity. |
| Reference | [1]. Quraishe S， et al. NAP (davunetide) rescues neuronal dysfunction in a Drosophila model of tauopathy. Mol Psychiatry. 2013;18(7):834-842. [2]. Zhang J， et al. Davunetide improves spatial learning and memory in Alzheimer’s disease-associated rats. Physiol Behav. 2017;174:67-73. [3]. Idan-Feldman A， et al. Davunetide (NAP) as a preventative treatment for central nervous system complications in a diabetes rat model. Neurobiol Dis. 2011;44(3):327-339. |
| Unit | Bottle |
| Specification | 1mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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