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My Cart> Cell Biology > Cell Detection > Cell Growth Factor > Recombinant Mouse Interleukin-12/IL-12Purity：≥95% as determined by reducing SDS-PAGE.
Storage：Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Appearance：Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
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| Appearance | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| Purity | ≥95% as determined by reducing SDS-PAGE. |
| Storage | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| Transport Condition | The product is shipped at ambient temperature. |
| Background | Mouse IL-12 is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit.Human and mouse IL-12 share 70% and 60% amino acid sequence identity in their p40 and p35 subunits，respectively.While mouse IL-12 is active on both human and mouse cells，human IL-12 is not active on murine cells.It is involved in the differentiation of naive T cells into Th1 cells.It is known as a T cell-stimulating factor，which can stimulate the growth and function of T cells.It stimulates the production of interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α) from T cells and natural killer (NK) cells，and reduces IL-4 mediated suppression of IFN-γ.T cells that produce IL-12 have a coreceptor，CD30，which is associated with IL-12 activity.IL-12 plays an important role in the activities of natural killer cells and T lymphocytes.IL-12 mediates enhancement of the cytotoxic activity of NK cells and CD8+ cytotoxic T lymphocytes. |
| Source | Human Cells |
| Solvent | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Endotoxin | Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test. |
| Unit | Piece |
| Specification | 10ug 50ug 500ug 1mg |
Recombinant Mouse Interleukin-12 is produced by our Mammalian expression system and the target gene encoding Met23-Ser335&Arg23-Ala215 is expressed.
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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