{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cell Cycle > Wogonin(10mM in DMSO,Sterile）CAS：632-85-9
Molecular Formula：C16H12O5
Molecular Weight：284.26
Storage：Stroe at -20℃，6 months.
Appearance：Sterile solution
Qty：
Size：
| CAS | 632-85-9 |
| Name | Wogonin(10mM in DMSO,Sterile） |
| Molecular Formula | C16H12O5 |
| Molecular Weight | 284.26 |
| Solubility | Please use according to your own experimental requirements. |
| Appearance | Sterile solution |
| Storage | Stroe at -20℃，6 months. |
| Target Point | CDK |
| Passage | Cell Cycle |
| Background | Wogonin is a flavonoid that inhibits the activity of CDK8 and Wnt signaling pathways. |
| Biological Activity | Wogonin is a naturally occurring mono-flavonoid， can inhibit the activity of CDK8 and Wnt， and exhibits anti-inflammatory and anti-tumor effects.[1-3] |
| IC50 | CDK8 |
| Data Literature Source | [1]. He L， et al. Wogonin induced G1 cell cycle arrest by regulating Wnt/β-catenin signaling pathway and inactivating CDK8 in human colorectal cancer carcinoma cells. Toxicology. 2013 Oct 4;312:36-47. [2]. Yang L， et al. Wogonin induces G1 phase arrest through inhibiting Cdk4 and cyclin D1 concomitant with an elevation in p21Cip1 in human cervical carcinoma HeLa cells. Biochem Cell Biol. 2009 Dec;87(6):933-42. [3]. Li HD， et al. Wogonin attenuates inflammation by activating PPAR-γ in alcoholic liver disease. Int Immunopharmacol. 2017 Sep;50:95-106. |
| Unit | bottle |
| Specification | 1ml |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no experimental images.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
