RKI-1447(10mM in DMSO,Sterile)
Cat.No:IR09001 Solarbio
CAS:1342278-01-6
Molecular Formula:C16H14N4O2S
Molecular Weight:326.37
Storage:Stroe at -20℃,6 months.
Appearance:Sterile solution
Qty:
Size:
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RKI-1447(10mM in DMSO,Sterile)CAS:1342278-01-6
Molecular Formula:C16H14N4O2S
Molecular Weight:326.37
Storage:Stroe at -20℃,6 months.
Appearance:Sterile solution
Qty:
Size:
CAS | 1342278-01-6 |
Name | RKI-1447(10mM in DMSO,Sterile) |
Molecular Formula | C16H14N4O2S |
Molecular Weight | 326.37 |
Solubility | Please use according to your own experimental requirements. |
Appearance | Sterile solution |
Storage | Stroe at -20℃,6 months. |
Target Point | ROCK |
Passage | Cytoskeleton; Cell Cycle;TGF-beta/Smad;Stem Cells |
Background | RKI-1447 is a potent ROCK1 and ROCK2 inhibitor. |
Biological Activity | RKI-1447 is a potent small molecule inhibitor of ROCK1 and ROCK2 with IC50 values of 14.5 nM and 6.2 nM, respectively[1]. |
Data Literature Source | [1]. Patel RA, et al. RKI-1447 is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer. Cancer Res. 2012 Oct 1;72(19):5025-34. |
Unit | bottle |
Specification | 1ml |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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