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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > DNA Damage & DNA Repai > Irinotecan Hydrochloride Trihydrate(10mM in DMSO,Sterile）CAS：136572-09-3
Molecular Formula：C33H38N4O6·HCl·3H2O
Molecular Weight：677.18
Storage：Stroe at -20℃，6 months.
Appearance：Sterile solution
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| CAS | 136572-09-3 |
| Name | Irinotecan Hydrochloride Trihydrate(10mM in DMSO,Sterile） |
| Molecular Formula | C33H38N4O6·HCl·3H2O |
| Molecular Weight | 677.18 |
| Solubility | Please use according to your own experimental requirements. |
| Appearance | Sterile solution |
| Storage | Stroe at -20℃，6 months. |
| Target Point | Topoisomerase |
| Passage | DNA Damage/DNA Repair |
| Background | Irinotecan hydrochloride trihydrate is a topoisomerase I (topoisomerase I) inhibitor with antitumor activity. |
| Biological Activity | Irinotecan hydrochloride trihydrate ((+)-Irinotecan hydrochloride trihydrate) is a topoisomerase I inhibitor with antitumor activity.[1-3] |
| Data Literature Source | [1]. Morales C， et al. Antitumoral effect of irinotecan (CPT-11) on an experimental model of malignant neuroectodermal tumor. J Neurooncol. 2002 Feb;56(3):219-26. [2]. Pavillard V， et al. Determinants of the cytotoxicity of irinotecan in two human colorectal tumor cell lines. Cancer Chemother Pharmacol. 2002 Apr;49(4):329-35. Epub 2002 Jan 30. [3]. Allegrini G， et al. Thrombospondin-1 plus irinotecan: a novel antiangiogenic-chemotherapeutic combination that inhibits the growth of advanced human colon tumor xenografts in mice. Cancer Chemother Pharmacol. 2004 Mar;53(3):261-6. Epub 2003 Dec 5. |
| Unit | bottle |
| Specification | 1ml |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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