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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > DNA Damage & DNA Repai > Teniposide(10mM in DMSO,Sterile）CAS：29767-20-2
Molecular Formula：C32H32O13S
Molecular Weight：656.65
Storage：Stroe at -20℃，6 months.
Appearance：Sterile solution
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| CAS | 29767-20-2 |
| Name | Teniposide(10mM in DMSO,Sterile） |
| Molecular Formula | C32H32O13S |
| Molecular Weight | 656.65 |
| Solubility | Please use according to your own experimental requirements. |
| Appearance | Sterile solution |
| Storage | Stroe at -20℃，6 months. |
| Target Point | Topoisomerase |
| Passage | DNA Damage/DNA Repair |
| Background | It acts by forming a ternary complex with topoisomerase II and DNA， acting in the late S phase or early G phase of the cell cycle. Related research for childhood acute lymphoblastic leukemia (ALL). |
| Biological Activity | Teniposide is a podophyllotoxin derivative， acts as a topoisomerase II inhibitor， and used as a chemotherapeutic agent.[1-3] |
| Data Literature Source | [1]. Attia SM， et al. Molecular cytogenetic evaluation of the aneugenic effects of teniposide in somatic and germinal cells of male mice. Mutagenesis. 2012 Jan;27(1):31-9. [2]. Li J， et al. Topoisomerase II trapping agent teniposide induces apoptosis and G2/M or S phase arrest of oral squamous cell carcinoma. World J Surg Oncol. 2006 Jul 6;4:41. [3]. Sun YC， et al. MiR-181b sensitizes glioma cells to teniposide by targeting MDM2. BMC Cancer. 2014 Aug 25;14:611. |
| Unit | bottle |
| Specification | 1ml |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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