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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > JAK/STAT > Artesunate(10mM in DMSO,Sterile）CAS：88495-63-0
Molecular Formula：C19H28O8
Molecular Weight：384.42
Storage：Stroe at -20℃，6 months.
Appearance：Sterile solution
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| CAS | 88495-63-0 |
| Name | Artesunate(10mM in DMSO,Sterile） |
| Molecular Formula | C19H28O8 |
| Molecular Weight | 384.42 |
| Solubility | Please use according to your own experimental requirements. |
| Appearance | Sterile solution |
| Storage | Stroe at -20℃，6 months. |
| Target Point | STAT3;exported protein 1 (EXP1) |
| Passage | JAK/STAT Signaling |
| Background | Artesunate is an inhibitor of STAT-3 and EXP1. |
| Biological Activity | Artesunate is an inhibitor of both STAT-3 and exported protein 1 (EXP1).[1-3] |
| Data Literature Source | [1]. Ilamathi M， et al. Artesunate as an Anti-Cancer Agent Targets Stat-3 and Favorably Suppresses Hepatocellular Carcinoma. Curr Top Med Chem. 2016;16(22):2453-63. [2]. Lisewski AM， et al. Supergenomic network compression and the discovery of EXP1 as a glutathione transferase inhibited by artesunate. Cell. 2014 Aug 14;158(4):916-928. [3]. Wang B， et al. Artesunate sensitizes ovarian cancer cells to cisplatin by downregulating RAD51. Cancer Biol Ther. 2015;16(10):1548-56. |
| Unit | bottle |
| Specification | 1ml |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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