{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > NF-κB > Andrographolide(10mM in DMSO,Sterile）CAS：5508-58-7
Molecular Formula：C20H30O5
Molecular Weight：350.45
Storage：Stroe at -20℃，6 months.
Appearance：Sterile solution
Qty：
Size：
| CAS | 5508-58-7 |
| Name | Andrographolide(10mM in DMSO,Sterile） |
| Molecular Formula | C20H30O5 |
| Molecular Weight | 350.45 |
| Solubility | Please use according to your own experimental requirements. |
| Appearance | Sterile solution |
| Storage | Stroe at -20℃，6 months. |
| Target Point | NF-κB |
| Passage | NF-κB |
| Background | Andrographolide is an NF-κB inhibitor that inhibits NF-κB activation by covalently modifying the cysteine ??residue of p50 in endothelial cells without affecting IκBα degradation or p50/p65 nuclear translocation. |
| Biological Activity | Andrographolide is a NF-κB inhibitor， which inhibits NF-κB activation through covalent modification of a cysteine residue on p50 in endothelial cells without affecting IκBα degradation or p50/p65 nuclear translocation. Andrographolide has antiviral effects.[1-2] |
| Data Literature Source | [1]. Zhai ZJ， et al. Andrographolide suppresses RANKL-induced osteoclastogenesis in vitro and prevents inflammatory bone loss in vivo. Br J Pharmacol. 2014 Feb;171(3):663-75. [2]. Gupta S， et al. Broad-spectrum antiviral properties of andrographolide. Arch Virol. 2017 Mar;162(3):611-623. |
| Unit | bottle |
| Specification | 1ml |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no experimental images.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
