Your Position: Home > Small Molecule Compounds > Inhibitors & Antagonists & Agonists > PI3K/Akt/mTOR > AZD 8055(10mM in DMSO,Sterile）

AZD 8055(10mM in DMSO,Sterile）

Manual Download

Cat.No：IA20201 Solarbio

CAS：1009298-09-2

Molecular Formula：C₂₅H₃₁N₅O₄

Molecular Weight：465.54

Storage：Stroe at -20℃，6 months.

Appearance：Sterile solution

Qty：

Size：

Add to cart

Product Information Experimental Images Related Products Related Paper Technical Q&A

Product Information

CAS	1009298-09-2
Name	AZD 8055(10mM in DMSO,Sterile）
Molecular Formula	C₂₅H₃₁N₅O₄
Molecular Weight	465.54
Solubility	Please use according to your own experimental requirements.
Appearance	Sterile solution
Storage	Stroe at -20℃，6 months.
Target Point	mTOR
Passage	PI3K/Akt/mTOR
Background	AZD-8055 is an ATP-competitive mTOR inhibitor.
Biological Activity	AZD-8055 is a potent， selective， and orally bioavailable ATP-competitive mTOR kinase inhibitor with an IC50 of 0.8 nM. AZD-8055 inhibits both mTORC1 and mTORC2.[1-3]
Data Literature Source	[1]. Chresta CM， et al. AZD8055 is a potent， selective， and orally bioavailable ATP-competitive mammalian target of rapamycin kinase inhibitor with in vitro and in vivo antitumor activity. Cancer Res， 2010， 70(1)， 288-298. [2]. You W， et al. Inhibition of mammalian target of rapamycin attenuates early brain injury through modulating microglial polarization after experimental subarachnoid hemorrhage in rats. J Neurol Sci. 2016 Aug 15;367:224-31. [3]. Kawata T， et al. Dual inhibition of the mTORC1 and mTORC2 signaling pathways is a promising therapeutic target for adult T-cell leukemia. Cancer Sci. 2017 Oct 27.
Unit	bottle
Specification	1ml

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

Note：

1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.

2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.

3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.

Experimental Images

Technical Q&A

Q&A （Total 0 User Q&A）

There is not question and answer now, come and send an inquiry please.

My question

Rank：

My question：

Identifying code：
captcha