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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > (S)-crizotinibCAS：1374356-45-2
Molecular Formula：C21H22Cl2FN5O
Molecular Weight：450.34
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 1374356-45-2 |
| Name | (S)-crizotinib |
| Molecular Formula | C21H22Cl2FN5O |
| Molecular Weight | 450.34 |
| Solubility | Soluble in DMSO ≥1mg/mL |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| Target Point | MTH1 |
| Passage | DNA Damage/DNA Repair |
| Background | (S)-Crizotinib is a potent selective MTH1 (mutT homolog) inhibitor that induces an increase in DNA single strand breaks by inhibiting MTH1 from disrupting nucleotide library homeostasis， activates DNA repair in human colon cancer cells， and effectively inhibits tumor growth in animal models. |
| Unit | Bottle |
| Specification | 1mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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