Bergamotine
Cat.No:IB8310 Solarbio
CAS:7380-40-7
Purity:HPLC≥98%
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Purity:HPLC≥98%
Qty:
Size:
CAS | 7380-40-7 |
Name | Bergamotine |
Purity | HPLC≥98% |
Target Point | Cytochrome P450 |
Passage | Metabolic Enzyme&Protease |
Background | Bergamottin is a potent competitive CYP1A1 inhibitor. |
Biological Activity | Bergamottin is a potent and competitive CYP1A1 inhibitor with a Ki of 10.703 nM.[1-2] |
Data Literature Source | [1]. Olguín-Reyes S, et al. Bergamottin is a competitive inhibitor of CYP1A1 and is antimutagenic in the Ames test. Food Chem Toxicol. 2012 Sep;50(9):3094-9. [2]. Wu HJ, et al. Bergamottin isolated from Citrus bergamia exerts in vitro and in vivo antitumor activity in lung adenocarcinoma through the induction of apoptosis, cell cycle arrest, mitochondrial membrane potential loss and inhibition of cell migration and invasion. Oncol Rep. 2016 Jul;36(1):324-32. |
Unit | Bottle |
Specification | 20mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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