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My CartReactivity：Human
Application：WB,IHC
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：5972
Purity：REN
Qty：
Size：
| Name | Anti-REN Polyclonal Antibody |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | WB 1:1000-3000.IHC 1:50-200. |
| Target | Rabbit |
| Background | This gene encodes renin， an aspartic protease that is secreted by the kidneys. Renin is a part of the renin-angiotensin-aldosterone system involved in regulation of blood pressure， and electrolyte balance. This enzyme catalyzes the first step in the activation pathway of angiotensinogen by cleaving angiotensinogen to form angiotensin I， which is then converted to angiotensin II by angiotensin I converting enzyme. This cascade can result in aldosterone release， narrowing of blood vessels， and increase in blood pressure as angiotension II is a vasoconstrictive peptide. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described， but their full-length nature has not been determined. Mutations in this gene have been shown to cause hyperuricemic nephropathy familial juvenile 2， familial hyperproreninemia， and renal tubular dysgenesis. |
| Swiss Prot | P00797 |
| Gene ID | 5972 |
| Subcellular Location | Secreted |
| Immunogen | Recombinant protein of human REN |
| Public Immunogen Range | 57-407aa |
| Calculated MW | 45kDa |
| Purification Method | Octanoic acid-ammonium sulfate precipitation |
| Storage Buffer | PBS with 50% Glycerol， 0.03% Proclin300， 0.5% BSA， pH 7.3. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Purity | REN |
| Conjugation Concentration | bottle |
| Conjugation | 50kDa |
| Specification | 20ul 50ul 100ul |
| Reactivity | Human |
| Application | WB IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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