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Storage:Store at RT，avoid light，6 months
Product Introduction:
Amyloid is a kind of extracellular acidophilic substance with no fixed shape, which can exist in different tissues and organs, resulting in diseases called amyloidosis. Amyloid is mainly composed of proteins, most of which are arranged in reverse β - fold structure. At present, research has found that the traditional methyl violet staining method has low sensitivity and poor specificity. The classic and effective method is Congo red staining.In 1922, Bennhold found that Congo red can be used to identify starch like substances in vivo, and applied to tissue sections.Later, after Highman's improvement, the dyeing effect was better.
The Congo Red Amyloid Stain Kit (Highman Method) mainly consists of Congo Red staining solution, hematoxylin staining solution, etc. and requires alkaline differentiation. The staining principle is that amyloid substances have a greater affinity for Congo red than other tissue structures, and their hydroxyl groups bind with the amino groups of Congo red, thereby dyeing amyloid substances red.
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