α-Cyclodextrin

Physical properties: white powder; Dissolved in water, it is a colorless clarified liquid with a reference concentration of 10mg/ml.

Uses: Biochemical research. Complexing agent, enzyme activity study, tissue culture agent.

The molecular structure of cyclodextrin is formed by more than 6 dextroses connected by α-1, 4 glucoside bonds in a barrel-like shape. A hydrophobic cavity is formed in the barrel, which can absorb hydrophobic small molecules or groups of a certain size and shape to form a stable non-covalent complex. Cyclodextrins can bind with many kinds of guest because of their special structure of hydrophilic outside, hydrophobic inside and excellent non-toxic properties. Cyclodextrins that consist of six, seven, and eight glucose monomers connected by alpha-1, 4-glucoside bonds are called α-cyclodextrins, β-cyclodextrins, and γ-cyclodextrins. β-cyclodextrin is one of the most effective inclusion materials known, the most widely used of the three types, and has been approved by the U.S. Food and Drug Administration.

1, α-cyclodextrin: six sugars, molecular weight is 972.86. Hexagonal flake or acicular crystal. Specific rotation [a]D+150.50

2, β-cyclodextrin: seven sugars, molecular weight is 1135. White powdery crystal. There are holes in the molecular ring structure, hole diameter 0.7-0.8nm, and various organic compounds can be formed. 1g is soluble in 18.5ml water. Specific rotation [a]D+162.00

3, gamma-cyclodextrin: eight sugars, molecular weight is 1297.14. Tetragonal or rectangular rod-like crystals. Melting point 267℃ (decomposition). Specific rotation [a]D+177.40

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Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

Note：

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