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CAS:5108-96-3
Storage:RT.
Purity:≥99.0%
Product Introduction：
Recombinant Human Ephrin Type-B Receptor 1 is produced by our Mammalian expression system and the target gene encoding Met18-Pro540 is expressed with a human IgG1 Fc tag at the C-terminus.
Nickname：
Ephrin Type-B Receptor 1; ELK; EPH Tyrosine Kinase 2; EPH-Like Kinase 6; EK6; hEK6; Neuronally-Expressed EPH; Related Tyrosine Kinase; NET; Tyrosine-Protein Kinase Receptor EPH-2; EPHB1; ELK; EPHT2; HEK6
Molecular Weight：
85.6 KDa
Apparent Molecular Weight：
85-110 KDa, reducing conditions
Dosage form description：
Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Endotoxin：
Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.
Redissolve:
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Storage：
Lyophilized protein should be stored at ≤ -20℃, stable for one year after receipt.
Reconstituted protein solution can be stored at 2-8℃ for 2-7 days.
Aliquots of reconstituted samples are stable at ≤ -20℃ for 3 months.
Transportation：
The product is shipped at ambient temperature.
Upon receipt, store it immediately at the temperature listed below.
Product background：
Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases that is involved in embryonic nervous and vascular system development. EPHB1/EPHT2 contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile α motif) domain. EPHB1 could stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner, which also correlated with its association with Grb7, an adaptor molecule implicated in the regulation of cell migration. It binds to ephrin-B1, ephrin-B2 and ephrin-B3. EPHB1 plays an important roles in diverse biological processes including nervous system development, angiogenesis, and neural synapsis formation and maturation and may be involved in cell-cell interactions in the nervous system.
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