GoldView II is a new anthocyanine nucleic acid dye that can replace Ethidium bromide (EB). When using agarose electrophoresis to detect DNA, GoldView II can produce a strong fluorescence signal after binding with nucleic acid, which is 5-10 times more sensitive than EB, and is used in exactly the same way. After combining with nucleic acid, GoldView II has a maximum absorption peak of 497nm, in addition, it also has a strong absorption peak at 254nm, and the emission wavelength is 520nm. Double-stranded DNA shows green fluorescence under ultraviolet transmitted light, and it can also be used to dye RNA.
The results of mutagenicity were negative by Ames test, micronucleus test of polychromatic erythrocytes in mouse bone marrow and chromosome aberration test of spermatocyte in mouse testis. Ethidium bromide (EB) is a potent carcinogen. Therefore, Goldview II is a wise alternative to EB.
This product is DMSO dissolved, solid at low temperature, and can be melted at temperatures above 20 ° C.
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