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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > AcetaminophenCAS：103-90-2
Molecular Formula：C8H9NO2
Molecular Weight：151.16
Storage：Powder:2-8℃，2 years
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 103-90-2 |
| Name | Acetaminophen |
| Molecular Formula | C8H9NO2 |
| Molecular Weight | 151.16 |
| Solubility | Soluble in Water ≥5mg/mL;Soluble in DMSO ≥25mg/mL(This product is not stable in solution, it is recommended that you use it now) |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years |
| EC | EINECS 203-157-5 |
| MDL | MFCD00002328 |
| SMILES | O=C(C)NC1=CC=C(O)C=C1 |
| InChIKey | RZVAJINKPMORJF-UHFFFAOYSA-N |
| InChI | InChI=1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10) |
| PubChem CID | 1983 |
| Target Point | COX-2 |
| Passage | Immunology & Inflammation |
| Background | Acetaminophen is a selective cyclooxygenase-2 (COX-2) inhibitor and a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor. |
| Biological Activity | Acetaminophen (paracetamol) 是选择性环氧合酶-2 (COX-2) 的抑制剂[1-3]。 |
| IC50 | IC50: COX-2:25.8μM[1-3]IC50: COX-1:113.7μM ) [1-3] |
| Data Literature Source | [1]. Hinz，B，et al. Acetaminophen (paracetamol) is a selective cyclooxygenase-2 inhibitor in man. FASEB J，2008. 22 (2) : p. 383-90. [2]. Dini M，et al. Lactobacillus fermentum Postbiotic-induced Autophagy as Potential Approach for Treatment ofAcetaminophen Hepatotoxicity. Front Microbiol. 2017 Apr 6; 8:594. [3]. Uchida NS，et al. Hepatoprotective Effect of Citral on Acetaminophen-Induced Liver Toxicity in Mice. Evid Based Complement Alternat Med. 2017; 2017:1796209 |
| Unit | Bottle |
| Specification | 100mg 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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