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Chemical Synthesis

SKU	Tongzhou Beijing	Haidian Beijing	Wuhan	Guangzhou
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CAS	58-61-7
Chinese Name	腺苷
English Name	Adenosine
Synonym	D-Adenosine;Adenine riboside
Unit	Bottle
Purity	HPLC≥98%
Molecular Formula	C₁₀H₁₃N₅O₄
Molecular Weight	267.24
Appearance	White to off-white solid
Storage	Powder : 2-8℃, 2 years; In solvent(mother liquid): -20℃, 1 month; -80℃, 6 months
Solubility	Soluble in DMSO≥10mg/ml
MDL	MFCD00005752
EC	EINECS 200-389-9
InChIKey	OIRDTQYFTABQOQ-KQYNXXCUSA-N
InChI	InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1
PubChem CID	60961
SMILES	NC1=C2C(N([C@H]3[C@H](O)[C@H](O)[C@@H](CO)O3)C=N2)=NC=N1
Description	Adenosine is an endogenous nucleoside distributed throughout human cells and is an important intermediate for the synthesis of adenosine triphosphate (ATP), adenine, adenylate, and adenosine arabinoside. It can directly enter the myocardium to be phosphorylated to generate adenylate.
Target Point	DNA/RNA Synthesis
Passage	Cell Cycle;DNA Damage/DNA Repair
Data Literature Source	[1]. Fredholm BB. Adenosine, an endogenous distress signal, modulates tissue damage and repair. Cell Death Differ. 2007;14(7):1315-1323. [2]. Borea PA, Gessi S, Merighi S, Vincenzi F, Varani K. Pharmacology of Adenosine Receptors: The State of the Art. Physiol Rev. 2018;98(3):1591-1625. [3]. Eltzschig HK. Adenosine: an old drug newly discovered. Anesthesiology. 2009;111(4):904-915. [4]. Zhou XT, et al. Inhibition of autophagy enhances adenosine induced apoptosis in human hepatoblastoma HepG2 cells. Oncol Rep. 2019;41(2):829-838.
Specification	50mg 10mM*1mL (in DMSO) 100mg