Arctiin
Cat.No:IA0460 Solarbio
CAS:20362-31-6
Molecular Formula:C27H34O11
Molecular Weight:534.55
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:HPLC≥98%
Appearance:White to off-white Solid
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ArctiinCAS:20362-31-6
Molecular Formula:C27H34O11
Molecular Weight:534.55
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:HPLC≥98%
Appearance:White to off-white Solid
Qty:
Size:
CAS | 20362-31-6 |
Name | Arctiin |
Molecular Formula | C27H34O11 |
Molecular Weight | 534.55 |
Solubility | Soluble in DMSO |
Purity | HPLC≥98% |
Appearance | White to off-white Solid |
Storage | Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year |
MDL | MFCD00870630 |
SMILES | O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](OC2=C(OC)C=C(C[C@H]3C(OC[C@@H]3CC4=CC(OC)=C(OC)C=C4)=O)C=C2)[C@@H]1O |
InChIKey | XOJVHLIYNSOZOO-SWOBOCGESA-N |
InChI | InChI=1S/C27H34O11/c1-33-18-6-4-14(10-20(18)34-2)8-16-13-36-26(32)17(16)9-15-5-7-19(21(11-15)35-3)37-27-25(31)24(30)23(29)22(12-28)38-27/h4-7,10-11,16-17,22-25,27-31H,8-9,12-13H2,1-3H3/t16-,17+,22+,23+,24-,25+,27+/m0/s1 |
PubChem CID | 100528 |
Target Point | Others |
Passage | Others |
Background | It is a plant lignan with anticancer activity. |
Biological Activity | Arctiin is a major lignan constituent of Arctium lappa and has anti-cancer properties in animal models.Arctiin down-regulates cyclin D1 protein expression and that this at least partially contributes to the anti-proliferative effect of arctiin.[1] Arctiin and its aglucone, arctigenin from the fruits of Arctium lappa L. showed potent in vitro antiviral activities against influenza A virus (A/NWS/33, H1N1) (IFV). Arctigenin was assumed to interfere with early event(s) of viral replication after viral penetration into cells, and to suppress the release of progeny viruses from the host cells. [2] |
Data Literature Source | [1]. Matsuzaki Y,Koyama M,Hitomi T,Yokota T,Kawanaka M,Nishikawa A,Germain D,Sakai T. Arctiin induces cell growth inhibition through the down-regulation of cyclin D1 expression. Oncol Rep. 2008 Mar;19(3):721-7. [2]. Hayashi K,Narutaki K,Nagaoka Y,Hayashi T,Uesato S. Therapeutic effect of arctiin and arctigenin in immunocompetent and immunocompromised mice infected with influenza A virus. Biol Pharm Bull. 2010;33(7):1199-205. |
Unit | Bottle |
Specification | 50mg 10mM*1mL in DMSO 100mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
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