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Acetylsalicylic acid
CAS:50-78-2
Storage:Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity:HPLC≥98%
Appearance:White to off-white Solid
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Acetylsalicylic acid, a derivative of salicylic acid, is an irreversible inhibitor of COX1 and COX2. Irreversible acetylation with serine residues at 530 of the COX-1 active site polypeptide chain in cyclooxygenase (COX) leads to COX inactivation, which then blocks the conversion of AA to thromboxane A2 (TXA2) and inhibits PLT aggregation. COXs is a key rate-limiting enzyme in the production of TXA2 and prostaglandin I2 (PGI2) by AA, and there are two forms of COX-1 and COX-2 in the human body, COX-1 is inherent to PLT.
Remark：
These protocols are for reference only. Solarbio does not independently validate these
methods.
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