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Your Position: Home > Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > COX > Acetylsalicylic acid
Acetylsalicylic acid

CAS:50-78-2

Appearance:White to off-white solid

Storage:Powder : 2-8℃, 2 years; In solvent(mother liquid): -20℃, 1 month; -80℃, 6 months

Purity:HPLC≥98%

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Acetylsalicylic acid
Cat.No：
IA0550
Brand：
Solarbio
SKU Tongzhou Beijing Haidian Beijing Wuhan Guangzhou
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Product Information Related Products Related Paper COA Technical Q&A

Acetylsalicylic acid, a derivative of salicylic acid, is an irreversible inhibitor of COX1 and COX2. Irreversible acetylation with serine residues at 530 of the COX-1 active site polypeptide chain in cyclooxygenase (COX) leads to COX inactivation, which then blocks the conversion of AA to thromboxane A2 (TXA2) and inhibits PLT aggregation. COXs is a key rate-limiting enzyme in the production of TXA2 and prostaglandin I2 (PGI2) by AA, and there are two forms of COX-1 and COX-2 in the human body, COX-1 is inherent to PLT.

Remark：
These protocols are for reference only. Solarbio does not independently validate these methods.

Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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Gegentana, et al. J Ethnopharmacol. 2020 Aug 10;258:112886.
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