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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cell Cycle > 5-BrdUCAS：59-14-3
Molecular Formula：C9H11BrN2O5
Molecular Weight：307.1
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥99%
Appearance：White to off-white Solid
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| CAS | 59-14-3 |
| Name | 5-BrdU |
| Molecular Formula | C9H11BrN2O5 |
| Molecular Weight | 307.1 |
| Solubility | Soluble in DMSO ≥50mg/mL |
| Purity | HPLC≥99% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 200-415-9 |
| MDL | MFCD00006529 |
| SMILES | OC[C@@H]1[C@H](C[C@H](N2C(NC(C(Br)=C2)=O)=O)O1)O |
| InChIKey | WOVKYSAHUYNSMH-RRKCRQDMSA-N |
| InChI | InChI=1S/C9H11BrN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1 |
| PubChem CID | 6035 |
| Target Point | DNA/RNA Synthesis |
| Passage | Cell Cycle;DNA Damage/DNA Repair |
| Background | 5-BrdU is a nucleoside analog that competes with thymidine for incorporation into DNA. |
| Biological Activity | 5-BrdU是一种核苷类似物，可与胸苷竞争掺入DNA。 5-BrdU通常用于检测增殖细胞。[1-2] |
| Data Literature Source | [1]. Levkoff LH，et al. Bromodeoxyuridine inhibits cancer cell proliferation in vitro and in vivo. Neoplasia. 2008 Aug;10(8):804-16. [2]. Rothaeusler K，et al. Assessment of cell proliferation by 5-bromodeoxyuridine (BrdU) labeling for multicolor flow cytometry. Curr Protoc Cytom. 2007 Apr;Chapter 7:Unit7.31 |
| Unit | Bottle |
| Specification | 100mg 10mM*1mL in DMSO 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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Shao L, et al. Stem Cell Res Ther. 2018 Aug 14;9(1):219.
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