Products
Ginsenoside Rb1

CAS:41753-43-9

Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year

Purity:HPLC≥98%

Appearance:White to off-white Solid

Ginsenoside Rb1
Cat.No:
IG0180
Brand:
Solarbio
SKU Tongzhou Beijing Haidian Beijing Wuhan Guangzhou
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Examples of using this product(for reference only)

In Vitro:

Cell (hair follicles, 10 μg/ml Ginsenoside Rb1, 9d; DPCs, 10 μg/ml Ginsenoside Rb1, 96 h):

Each group contained 15 hair follicles and they were cultured with or without 10 μg/ml of ginsenoside Rb1 in a humidified incubator at 37 ℃ and 5% CO2 for 9 days.    The culture medium was changed every two days and the measurement of lengths of the hair follicles were performed by blinding observer who did not know the experimental groups using a micrometer under an inverted microscope every three days.

Then the DPCs were seeded to 6 well-plates and cultured with 0 and 10 μg/ml ginsenoside Rb1 for 96 h. For studying the effects of ginsenoside Rb1 on PI3K/AKT/GSK-3β pathway, DPCs were also treated with the PI3K inhibitor 10 μM LY294002 or 10 μg/ml ginsenoside Rb1 + 10 μM LY294002, respectively. In the ginsenoside Rb1 and LY294002 combination group, the cells were pre-treated with 10 μM LY294002 for 1 h, then treated with 10 μg/ml ginsenoside Rb1 and cultured for another 96 h.

Reference:

Zhang H, Su Y, Wang J, Gao Y, Yang F, Li G, Shi Q. Ginsenoside Rb1 promotes the growth of mink hair follicle via PI3K/AKT/GSK-3β signaling pathway. Life Sci. 2019 Jul 15;229:210-218. doi: 10.1016/j.lfs.2019.05.033. Epub 2019 May 16. PMID: 31102746.

Remark:
These protocols are for reference only. Solarbio does not independently validate these methods.

Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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