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CAS:22427-39-0
Appearance:White to yellow solid
Storage:Powder : 2-8℃, 2 years; In solvent(mother liquid): -20℃, 1 month; -80℃, 6 months
Purity:HPLC≥98%
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Examples of using this product（for reference only）
In Vivo:
Rat（healthy male SD rats of SPF class, weighing 200 ± 25 g；0.5 mL 12–5 g/mL Ginsenoside Rg1，Gavage/d，8weeks）:
The rats were randomly divided into 3 groups (40/group): normal rats group (NC); DR rats (Model); g1-treated DR rats group (Rg1). The rats were acclimatized and housed for 1 week before the experiment, and they were fed and watered ad libitum. The rats in the diabetic group were fasted for 12 h before modeling and weighed before the experiment. In the diabetic group, freshly prepared STZ in bufer (55 mg/kg) was injected once into the left lower abdominal cavity, and the rats ate and drank normally after the injection. After the rats were injected with STZ for 48 h, the blood glucose and body weight were measured. Additionally, in the diabetic rat models, blood glucose >16.7 mmol/L, polyuria, and polyphagia were considered. The blood glucose and body weight of the rats were observed once every 2 weeks. In the Rg1 group, gavage was started on the day of modeling, and 0.5 mL (12–5 g/ml) of Rg1 solution (Solarbio, Beijing,China) was given by gavage every day, while the same dose of saline was given to the model and NC groups. The rats were sacrifced 8 weeks after modeling, and fresh retinal specimens were removed and preserved for the relevant assays.
Reference：
Xue L, Hu M, Li J, Li Y, Zhu Q, Zhou G, Zhang X, Zhou Y, Zhang J, Ding P. Ginsenoside Rg1 Inhibits High Glucose-Induced Proliferation, Migration, and Angiogenesis in Retinal Endothelial Cells by Regulating the lncRNA SNHG7/miR-2116-5p/SIRT3 Axis. J Oncol. 2022 Dec 3;2022:6184631. doi: 10.1155/2022/6184631. PMID: 36510610; PMCID: PMC9741534.
