Ibuprofen_COX_Immunology & Inflammation_Inhibitors & Antagonists & Agonists_Small Molecule Compounds

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SKU	Tongzhou Beijing	Haidian Beijing	Wuhan	Guangzhou
II0020-100mg	Inquiry	Inquiry	Inquiry	Inquiry
II0020-50mg	Inquiry	Inquiry	Inquiry	Inquiry
II0020-1ml	Inquiry	Inquiry	Inquiry	Inquiry

CAS	15687-27-1
Chinese Name	布洛芬
English Name	Ibuprofen
Synonym	布洛芬;4-异丁基-Α-甲基苯乙酸;对异丁苯丙酸;异丁苯丙酸;芬必得;拔怒风;Azaperon;Azaperone;
Unit	Bottle
Purity	HPLC≥98%
Molecular Formula	C₁₃H₁₈O₂
Molecular Weight	206.28
Appearance	White to off-white solid
Storage	Powder : 2-8℃, 2 years; In solvent(mother liquid): -20℃, 1 month; -80℃, 6 months
Solubility	Soluble in DMSO
EC	EINECS 239-784-6
MDL	MFCD00010393
InChIKey	HEFNNWSXXWATRW-UHFFFAOYSA-N
InChI	InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)
PubChem CID	3672
SMILES	OC(C(C1=CC=C(CC(C)C)C=C1)C)=O
Description	I-BRD9 is a potent and selective BRD9 inhibitor.
Target Point	COX
Passage	Immunology & Inflammation
Data Literature Source	[1]. Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61(1):2-7. [2]. Palayoor ST, et al. Constitutive activation of IkappaB kinase alpha and NF-kappaB in prostate cancer cells is inhibited by ibuprofen. Oncogene. 1999 Dec 2;18(51):7389-94. [3]. Khwaja F, et al. Ibuprofen inhibits survival of bladder cancer cells by induced expression of the p75NTR tumor suppressor protein. Cancer Res. 2004 Sep 1;64(17):6207-13. [4]. Rao GH, et al. Ibuprofen protects platelet cyclooxygenase from irreversible inhibition by aspirin. Arteriosclerosis. 1983 Jul-Aug;3(4):383-8. [5]. Driban JB, et al. Joint inflammation and early degeneration induced by high-force reaching are attenuated by ibuprofen in an animal model of work-related musculoskeletal disorder. J Biomed Biotechnol. 2011;2011:691412
Specification	50mg 100mg 10mM*1mL (in DMSO)