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My CartCAS：53-84-9
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to yellow Solid
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| CAS | 53-84-9 |
| Name | NAD+ |
| Molecular Formula | C21H27N7O14P2 |
| Molecular Weight | 663.43 |
| Solubility | Soluble in Water ≥100mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to yellow Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 200-184-4 |
| MDL | MFCD00036253 |
| SMILES | O[C@H]([C@@H]1O)[C@@H](O[C@@H]1COP(OP(OC[C@H]2O[C@@H]([N+]3=CC=CC(C(N)=O)=C3)[C@H](O)[C@@H]2O)([O-])=O)(O)=O)N4C(N=CN=C5N)=C5N=C4 |
| InChIKey | BAWFJGJZGIEFAR-NNYOXOHSSA-N |
| InChI | InChI=1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1 |
| PubChem CID | 5892 |
| Background | NAD+, nicotinamide adenine dinucleotide, is a coenzyme that transfers hydrogen ions. NAD+ is the oxidized form of NADH. |
| Biological Activity | NAD+ 即烟酰胺腺嘌呤二核苷酸，是一种转递氢离子的辅酶。NAD+是NADH的氧化形式[1-3]。 |
| In Vitro | NAD +是由核糖基烟酰胺5'-二磷酸组成的辅酶，其通过焦磷酸键连接至腺苷5'-磷酸。 NAD +是NADH的氧化形式[1]。 NAD +在自然界中广泛存在，并且参与许多酶促反应，其中它通过交替氧化(NAD +)和还原(Nadide)而用作电子载体[2]。 |
| In Vivo | 口服NAD +补充剂已用于对抗单纯疲劳以及诸如慢性疲劳综合征和纤维肌痛等神秘和能量消耗障碍[3]。 |
| Data Literature Source | [1]. Viollet，B.，et al.，Cellular and molecular mechanisms of metformin: an overview. Clin Sci (Lond)，2012. 122(6): p. 253-70. [2]. Brandt，U.，Energy converting NADH:quinone oxidoreductase (complex I). Annu Rev Biochem，2006. 75: p. 69-92. [3]. Kussmaul，L. and J. Hirst，The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria. Proc Natl Acad Sci U S A，2006. 103(20): p. 7607-12. |
| Unit | Bottle |
| Specification | 200mg 10mM*1mL in Water 1g |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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Wang J, et al. Antioxidants (Basel, Switzerland),2021,10(2):
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