Novobiocin Sodium
CAS:1476-53-5
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:HPLC≥90%
Appearance:White to yellow Solid
是一种抗生素,源于链霉菌,对革兰氏阳性菌有较强的抗菌活性,但由于外膜中含有脂多糖,对革兰氏阴性菌的抗菌活性有限。也是一个强效的DNA gyrase抑制剂通过结合ATP结合位点在ATP酶亚基。与 Hsp90的c端结合,轻微诱导 Hsp90依赖的client 蛋白的降解。
Remark:
These protocols are for reference only. Solarbio does not independently validate these
methods.
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