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CAS:61825-94-3
Storage:Powder:2-8℃，2 years
Purity:HPLC≥98%
Appearance:White to off-white Solid
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Examples of using this product（for reference only）
In Vivo:
Mice ( 1.5 months old, male ICR mice; 5 mg/kg oxaliplatin; I.P；once a day for 10 d)：
According to the report, the CRC model mice were prepared by the established method, in which azoxymethane (AOM) and dextran sodium sulfate (DSS) were used. Mice were intraperitoneally injected with 2 mg/kg AOM once at the first week. Then the mice were given an aqueous solution of dissolved 2.5% DSS for one week. Two weeks later, mice received AOM injection again, followed by drinking DSS solution. The cycles were carried out for 5 rounds, with each round for 4 weeks. When the mice showed emaciation and hematochezia, they were randomly divided into four groups. The mice in one group were given PBS as model control, and the second group was intraperitoneally injected with 5 mg/kg oxaliplatin (positive control) once a day for 10 d. The other two groups were orally administered 5 mg/kg ph-ph+ and 5 mg/kg ph-ph+/SDC/EPC daily for 10 d.
Reference：
Zhang Y, Zhao Z, Li J, Wang Q, Fan Z, Yuan Z, Feng Y, Fu A. Treatment of colorectal cancer by anticancer and antibacterial effects of hemiprotonic phenanthroline-phenanthroline+ with nanomicelle delivery. Asian J Pharm Sci. 2023 May;18(3):100801. doi: 10.1016/j.ajps.2023.100801. Epub 2023 Mar 28. PMID: 37274926; PMCID: PMC10232661.
