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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > GPCR & G Protein > (20S)-ProtopanaxatriolCAS：34080-08-5
Molecular Formula：C30H52O4
Molecular Weight：476.73
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 34080-08-5 |
| Name | (20S)-Protopanaxatriol |
| Molecular Formula | C30H52O4 |
| Molecular Weight | 476.73 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD11041271 |
| SMILES | C[C@]([C@@](C[C@H]1O)([H])[C@]2(CC[C@@H]3O)C)(C[C@H](O)[C@@]2([H])C3(C)C)[C@]4([C@@]1([H])[C@]([C@@](C)(O)CC/C=C(C)/C)([H])CC4)C |
| InChIKey | SHCBCKBYTHZQGZ-CJPZEJHVSA-N |
| InChI | InChI=1S/C30H52O4/c1-18(2)10-9-13-30(8,34)19-11-15-28(6)24(19)20(31)16-22-27(5)14-12-23(33)26(3,4)25(27)21(32)17-29(22,28)7/h10,19-25,31-34H,9,11-17H2,1-8H3/t19-,20+,21-,22+,23-,24-,25-,27+,28+,29+,30-/m0/s1 |
| PubChem CID | 11468733 |
| Target Point | Glucocorticoid Receptor (GR, or GCR) |
| Passage | GPCR & G Protein |
| Background | It is a metabolite of ginsenoside, acts through glucocorticoid receptor and oestrogen receptor, and is an inhibitor of LXRα. |
| Biological Activity | (20S)-Protopanaxatriol 是人参皂苷的代谢物，通过 glucocorticoid receptor 和 oestrogen receptor 起作用，同时为 LXRα 的抑制剂。[1-2] |
| Data Literature Source | [1]. Leung KW， et al. Protopanaxadiol and protopanaxatriol bind to glucocorticoid and oestrogen receptors in endothelial cells. Br J Pharmacol. 2009 Feb; 156 (4) :626-37. [2]. Oh GS， et al. 20 (S) -protopanaxatriol inhibits liver X receptor α-mediated expression of lipogenic genes in hepatocytes. J Pharmacol Sci. 2015 Jun; 128 (2) :71-7. |
| Unit | Bottle |
| Specification | 10mg 10mM*1mL in DMSO 20mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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