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Your Position: Home > Small Molecule Compounds > Inhibitors & Antagonists & Agonists > PI3K/Akt/mTOR > Phosphoinositide 3-Kinase/PI3K > Quercetin
Quercetin

CAS:117-39-5

Appearance:Light yellow to yellow solid

Storage:Powder : 2-8℃, 2 years; In solvent(mother liquid): -20℃, 1 month; -80℃, 6 months

Purity:HPLC≥98%

   Manual Download
Quercetin
Cat.No：
IQ0010
Brand：
Solarbio
SKU Tongzhou Beijing Haidian Beijing Wuhan Guangzhou
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Product Information Related Products Related Paper COA Technical Q&A


Examples of using this product（for reference only）

In Vitro:

Cell（The human gastric mucosal epithelial cell line GES-1, 0~100 μM Que, 24h ）:

100 mg of quercetin (IQ0010, Solarbio) dissolved in 2 ml of DMSO, the molar concentration of the mother liquor is 165.43 mM, and different concentrations of quercetin are prepared according to the steps in the product specification. When the confluence reached 80–90%, the cells were treated for 24 h with different concentration of quercetin (Que, 0, 12.5, 25, 50, and 100 μM), followed by addition 200 μM H2O2 treatment. The cells in control group were treated with normal medium. The cells in the model group were only treated with 200 μM H2O2. The cell proliferation, apoptosis, inflammation, mitochondrial function, barrier, and the activity of PI3K/AKT pathway were then evaluated. Subsequently, GES-1 cells were treated with 10 μM LY294002, the inhibition of PI3K,combination with/without 25 μM Que, followed by treating with 200 μM H2O2.

Reference：

Yao X, Mei Y, Mao W. Quercetin Improves Mitochondrial Function and Inflammation in H2O2-Induced Oxidative Stress Damage in the Gastric Mucosal Epithelial Cell by Regulating the PI3K/AKT Signaling Pathway. Evid Based Complement Alternat Med. 2021 Nov 27;2021:1386078. doi: 10.1155/2021/1386078. PMID: 34873406; PMCID: PMC8643250.

Remark：
These protocols are for reference only. Solarbio does not independently validate these methods.

Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Experimental Images
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Yao X, Mei Y, Mao W. Evid Based Complement Alternat Med. 2021 Nov 27;20211386078.
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