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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > ER Stress > Sodium 4-phenylbutyrateCAS：1716-12-7
Molecular Formula：C10H11NaO2
Molecular Weight：186.18
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 1716-12-7 |
| Name | Sodium 4-phenylbutyrate |
| Molecular Formula | C10H11NaO2 |
| Molecular Weight | 186.18 |
| Solubility | Soluble in Water |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 605-612-7 |
| MDL | MFCD00800247 |
| SMILES | [O-]C(CCCC1=CC=CC=C1)=O.[Na+] |
| InChIKey | VPZRWNZGLKXFOE-UHFFFAOYSA-M |
| InChI | InChI=1S/C10H12O2.Na/c11-10(12)8-4-7-9-5-2-1-3-6-9;/h1-3,5-6H,4,7-8H2,(H,11,12);/q;+1/p-1 |
| PubChem CID | 5258 |
| Target Point | HDAC |
| Passage | DNA Damage/DNA Repair;Epigenetics;NF-κB;ER Stress |
| Background | Sodium 4-phenylbutyrate is a histone deacetylase (HDAC) and endoplasmic reticulum stress (ER) inhibitor used in the study of diseases such as cancer and infection. |
| Biological Activity | Sodium phenylbutyrate 是一种组蛋白去乙酰化酶 (HDAC) 和内质网应激 (ER) 抑制剂，可用于癌症和感染等疾病的研究。[1-3] |
| Data Literature Source | [1]. Chang TH，et al. Enhanced growth inhibition by combination differentiation therapy with ligands of peroxisome proliferator-activated receptor-gamma and inhibitors of histone deacetylase in adenocarcinoma of the lung. Clin Cancer Res. 2002 Apr;8(4):1206-12. [2]. Frouco G，et，al. Sodium phenylbutyrate abrogates African swine fever virus replication by disrupting the virus-induced hypoacetylation status of histone H3K9/K14. Virus Res. 2017 Oct 15;242:24-29. [3]. Park HJ，et al. 4-Phenylbutyric acid protects against lipopolysaccharide-induced bone loss by modulating autophagy in osteoclasts. Biochem Pharmacol. 2018 May;151:9-17. |
| Unit | Bottle |
| Specification | 100mg 10mM*1mL in Water |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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