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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cell Cycle > 8-AzaguanineCAS：134-58-7
Molecular Formula：C4H4N6O
Molecular Weight：152.11
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to yellow Solid
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| CAS | 134-58-7 |
| Name | 8-Azaguanine |
| Molecular Formula | C4H4N6O |
| Molecular Weight | 152.11 |
| Solubility | Soluble in Water ≥10mg/mL(Need ultrasonic or add HCl/NaOH to help dissolve) ;Soluble in DMSO ＜ 1mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to yellow Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 205-148-1 |
| MDL | MFCD00056937 |
| SMILES | O=C1C(N=NN2)=C2N=C(N)N1 |
| InChIKey | LPXQRXLUHJKZIE-UHFFFAOYSA-N |
| InChI | InChI=1S/C4H4N6O/c5-4-6-2-1(3(11)7-4)8-10-9-2/h(H4,5,6,7,8,9,10,11) |
| PubChem CID | 135403646 |
| Target Point | DNA/RNA Synthesis |
| Passage | Cell Cycle;DNA Damage/DNA Repair |
| Background | 8-Azaguanine is a purine analogue that has antitumor activity. 8-Azaguanine is easily incorporated into ribonucleic acid， interferes with normal biosynthesis pathway， and thus inhibits cell growth， and can be used in the related research of anti-metabolic drugs. |
| Biological Activity | 8-Azaguanine 是显示抗肿瘤活性的嘌呤类似物[1]。 |
| Data Literature Source | [1]. Dourado M， et al. CD26/DPPIV expression and 8-azaguanine response in T-acute lymphoblastic leukaemia cell lines in culture. Pathophysiology. 2007 May; 14 (1) :3-10. |
| Unit | Bottle |
| Specification | 50mg 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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Ribavirin targets sugar transporter 6 to suppress acquisition and transmission of rice stripe tenuivirus by its vector Laodelphax striatellus
Click to check >>Author：Hajano JU; Raza A; Zhang L; Liu W; Wang X.
IF：4.1000
Publish_to：PEST MANAGEMENT SCIENCE
PMID：32542993
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