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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Metabolic Enzyme & Protease > AlizarinCAS：72-48-0
Molecular Formula：C14H8O4
Molecular Weight：240.21
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥95%
Appearance：Light yellow to yellow Solid
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| CAS | 72-48-0 |
| Name | Alizarin |
| Molecular Formula | C14H8O4 |
| Molecular Weight | 240.21 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥95% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 200-782-5 |
| MDL | MFCD00001201 |
| SMILES | O=C1C2=C(C=CC=C2)C(C3=CC=C(O)C(O)=C13)=O |
| InChIKey | RGCKGOZRHPZPFP-UHFFFAOYSA-N |
| InChI | InChI=1S/C14H8O4/c15-10-6-5-9-11(14(10)18)13(17)8-4-2-1-3-7(8)12(9)16/h1-6,15,18H |
| PubChem CID | 6293 |
| Target Point | Cytochrome P450 |
| Passage | Metabolic Enzyme&Protease |
| Background | Alizarin is a natural dye extracted from the roots of the madder plant. |
| Biological Activity | Alizarin (Anthraquinonic) 强效抑制P450亚型CYP1A1， CYP1A2和CYP1B1，IC50分别为6.2 μM， 10.0 μM and 2.7 μM，微弱抑制CYP2A6和CYP2E1，对CYP2C19，对CYP3A4和CYP3A5没有抑制作用。[1-2] |
| Data Literature Source | [1] Takahashi E，et al. Mutat Res，2002，508(1-2)，147-156. [2] Zhang J，et al. J Nutr Environ Med，1997，7(2)，79-89. |
| Unit | Bottle |
| Specification | 20mg 10mM*1mL in DMSO 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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