{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Others > CrotalineCAS：315-22-0
Molecular Formula：C16H23NO6
Molecular Weight：325.36
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 315-22-0 |
| Name | Crotaline |
| Molecular Formula | C16H23NO6 |
| Molecular Weight | 325.36 |
| Solubility | Soluble in DMSO ≥10mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 628-506-2 |
| MDL | MFCD00084656 |
| SMILES | O=C(O[C@]1([H])CCN2[C@]1([H])C(CO3)=CC2)[C@H](C)[C@@](C)(O)[C@@](C)(O)C3=O |
| InChIKey | QVCMHGGNRFRMAD-XFGHUUIASA-N |
| InChI | InChI=1S/C16H23NO6/c1-9-13(18)23-11-5-7-17-6-4-10(12(11)17)8-22-14(19)16(3,21)15(9,2)20/h4,9,11-12,20-21H,5-8H2,1-3H3/t9-,11+,12+,15+,16-/m0/s1 |
| PubChem CID | 9415 |
| Target Point | Others |
| Passage | Others |
| Background | It is a pyrrolizidine alkaloid, which has inhibitory effect on various tumors, and is considered to be an alkylating agent, which exerts anticancer activity through the alkylation of DNA. |
| Data Literature Source | [1]. Gomez-Arroyo JG， et al. The monocrotaline model of pulmonary hypertension in perspective. Am J Physiol Lung Cell Mol Physiol. 2012 Feb 15; 302 (4) :L363-9. [2]. Kusuma SS， et al. Antineoplastic activity of monocrotaline against hepatocellular carcinoma. Anticancer Agents Med Chem. 2014; 14 (9) :1237-48. [3]. Wilson DW， et， al. Mechanisms and pathology of monocrotaline pulmonary toxicity. Crit Rev Toxicol. 1992; 22 (5-6) :307-25. [4]. Nogueira-Ferreira R， et al. Exploring the monocrotaline animal model for the study of pulmonary arterial hypertension: A network approach. Pulm Pharmacol Ther. 2015 Dec; 35:8-16. [5]. Rafikova O，et al. Metabolic Changes Precede the Development of Pulmonary Hypertension in the Monocrotaline Exposed RatLung. PLoS One. 2016 Mar 3; 11 (3) :e0150480. |
| Unit | Bottle |
| Specification | 20mg 10mM*1mL in DMSO 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
