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CAS	481-49-2
Chinese Name	千金藤素
English Name	Cepharanthine
Synonym	NSC-623442;千金藤碱
Purity	HPLC≥98%
Molecular Formula	C₃₇H₃₈N₂O₆
Molecular Weight	606.71
Appearance	White to yellow solid
Storage	Powder : 2-8℃, 2 years; In solvent(mother liquid): -20℃, 1 month; -80℃, 6 months
Solubility	Soluble in DMSO≥10mg/ml
MDL	MFCD00210482
InChIKey	YVPXVXANRNDGTA-WDYNHAJCSA-N
InChI	InChI=1S/C37H38N2O6/c1-38-13-11-24-18-31(41-4)33-20-27(24)28(38)16-23-7-10-30(40-3)32(17-23)44-26-8-5-22(6-9-26)15-29-35-25(12-14-39(29)2)19-34-36(37(35)45-33)43-21-42-34/h5-10,17-20,28-29H,11-16,21H2,1-4H3/t28-,29+/m1/s1
PubChem CID	10206
SMILES	[H][C@]12N(C)CCC(C1=C3)=CC(OC)=C3OC4=C5C(OCO5)=CC6=C4[C@](N(C)CC6)([H])CC(C=C7)=CC=C7OC8=C(OC)C=CC(C2)=C8
Description	Cepharanthine, an alkaloid in Stephania cepharantha Hayata, has anti-inflammatory, antioxidant activity.
Target Point	TNF-α
Passage	Apoptosis
Data Literature Source	[1]. Hijikata A, et al. Evaluating cepharanthine analogues as natural drugs against SARS-CoV-2. FEBS Open Bio. 2022;12(1):285-294 [2]. Li S, Liu W, Chen Y, Wang L, An W, An X, Song L, Tong Y, Fan H, Lu C. Transcriptome analysis of cepharanthine against a SARS-CoV-2-related coronavirus. Brief Bioinform. 2021 Mar 22;22(2):1378-1386. [3]. Ohashi H, Watashi K, Saso W, Shionoya K, Iwanami S, Hirokawa T, Shirai T, Kanaya S, Ito Y, Kim KS, Nomura T, Suzuki T, Nishioka K, Ando S, Ejima K, Koizumi Y, Tanaka T, Aoki S, Kuramochi K, Suzuki T, Hashiguchi T, Maenaka K, Matano T, Muramatsu M, Saijo M, Aihara K, Iwami S, Takeda M, McKeating JA, Wakita T. Potential anti-COVID-19 agents, cepharanthine and nelfinavir, and their usage for combination treatment. iScience. 2021 Apr 23;24(4):102367.
Specification	20mg 10mM*1mL in DMSO 100mg