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SKU	Tongzhou Beijing	Haidian Beijing	Wuhan	Guangzhou
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English Name	Anti-Jak1 Monoclonal Antibody
Chinese Name	Janus激酶1,酪氨酸蛋白激酶1抗体
Host	Mouse
Clone Type	Monoclonal Antibody
Subtype	IgG1
Clone Number	7B1-B6-G7
Dilution Ratio	WB 1:500-1000. IP 1:20.
Target	Jak1
Synonyms	JAK 1, JAK 1A, JAK 1B, JAK1, JAK1A, JAK1B, Janus kinase 1 (a protein tyrosine kinase), Janus kinase 1, JTK3, Tyrosine protein kinase JAK 1, Tyrosine protein kinase JAK1, JAK1_HUMAN
Background	Janus kinase 1 (JAK1), is a member of a new class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The second phosphotransferase domain bears all the hallmarks of a protein kinase, although its structure differs significantly from that of the PTK and threonine/serine kinase family members. JAK1 is a large, widely expressed membrane-associated phosphoprotein. JAK1 is involved in the interferon-alpha/beta and -gamma signal transduction pathways. The reciprocal interdependence between JAK1 and TYK2 activities in the interferon-alpha pathway, and between JAK1 and JAK2 in the interferon-gamma pathway, may reflect a requirement for these kinases in the correct assembly of interferon receptor complexes.
Swiss Prot	P23458
Gene ID	3716
Subcellular Location	Endomembrane system Peripheral membrane protein
Immunogen	Recombinant protein of human Jak1
Calculated MW	133kDa
Purification Method	Affinity purification
Storage Buffer	PBS with 0.02% sodium azide，0.5% BSA，50% glycerol，pH7.3.
Storage	Store at -20℃. Avoid freeze / thaw cycles.
Unit	Piece
Specification	50ul 100ul
Reactivity	Rat Human
Application	IP WB