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My CartReactivity：Transfected
Application：WB
Clone Type：Monoclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：2099
Host：Mouse
Qty：
Size：
| Name | Anti-ESR1 Monoclonal Antibody |
| Host | Mouse |
| Clone Type | Monoclonal Antibody |
| Subtype | IgG2b |
| Clone Number | 6F11-C3-G6 |
| Dilution Ratio | WB 1:500-1000. |
| Target | ESR1 |
| Background | This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. |
| Swiss Prot | P03372 |
| Gene ID | 2099 |
| Subcellular Location | Cell membrane Cytoplasm Cytoplasmic side Cytoplasmic side Golgi apparatus Nucleus Peripheral membrane protein Single-pass type I membrane protein |
| Immunogen | Recombinant protein of human ESR1 |
| Public Immunogen Range | 153-348aa |
| Calculated MW | 66kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide，0.5% BSA，50% glycerol，pH7.3. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Unit | Piece |
| Specification | 50ul 100ul |
| Reactivity | Transfected |
| Application | WB |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Western blot analysis with ESR1 antibody diluted at 1:1000;Lane: Recombinant Estrogen Receptor alpha CHO-K1,CHO-K1.
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