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SKU	Tongzhou Beijing	Haidian Beijing	Wuhan	Guangzhou
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English Name	Anti-PTK2 Monoclonal Antibody
Chinese Name	粘附斑激酶抗体
Host	Mouse
Clone Type	Monoclonal Antibody
Subtype	IgG1
Clone Number	3D8-H11-E12
Dilution Ratio	WB 1:500-1000. IF 1:50-200. IP 1:20. ICC 1:50-200.
Target	PTK2
Synonyms	PTK2;FADK;FAK;FAK1;FRNK;PPP1R71;p125FAK;pp125FAK;focal adhesion kinase 1
Background	This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined.
Swiss Prot	Q05397
Gene ID	5747
Subcellular Location	Cell junction Cell membrane Cytoplasm Cytoplasmic side Nucleus Peripheral membrane protein cell cortex centrosome cytoskeleton focal adhesion microtubule organizing center
Immunogen	Recombinant protein of human PTK2
Calculated MW	40/49/63/99/121/114/119kDa
Purification Method	Affinity purification
Storage Buffer	PBS with 0.02% sodium azide，0.5% BSA，50% glycerol，pH7.3.
Storage	Store at -20℃. Avoid freeze / thaw cycles.
Unit	Piece
Specification	50ul 100ul
Reactivity	Human
Application	IP ICC IF WB