English Name |
Anti-RAD23B Monoclonal Antibody |
Chinese Name |
泛素受体RAD23b抗体 |
Target |
RAD23B |
Synonym |
hHR 23b, hHR23B, HR 23B, HR23B, mHR 23B, mHR23B, P58, RAD 23B, RAD23 (S. cerevisiae) homolog B, RAD23 homolog B (S. cerevisiae), RAD23 homolog B, RAD23 yeast homolog of B, RD23B_HUMAN, UV excision repair protein RAD23 homolog B, XP C repair complementing complex 58 kDa, XP C repair complementing complex 58 kDa protein, XP C repair complementing protein, XP-C repair-complementing complex 58 kDa protein, XPC repair complementing complex 58 kDa, XPC repair complementing complex 58 kDa protein, XPC repair complementing protein |
Backgroud |
The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2011] |
Swiss Prot |
P54727 |
Gene ID |
5887 |
Subcellular Localization |
Cytoplasm Nucleus |
Host |
Mouse |
Clone Type |
Monoclonal Antibody |
Subtype |
IgG2b |
Clone Number |
5H1-A10-A7 |
Protein MW |
43kDa |
Dilution Ratio |
WB 1:500-1000. IHC 1:50-100. IF 1:50-200. ICC 1:50-200. |
Immunogen |
Recombinant protein of human RAD23B |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: PBS with 0.02% sodium azide, 0.5% BSA, 50% glycerol, pH7.3. |
Storage |
Store at -20℃. Avoid freeze / thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Human Hamster Monkey Rat Mouse |
Application |
WB ICC IHC IF |
Specification |
50ul 100ul |