English Name |
Anti-Wnt3 Monoclonal Antibody |
Chinese Name |
Wnt3抗体 |
Target |
Wnt3 |
Synonym |
Int 4, INT4, MGC131950, MGC138321, MGC138323, Proto-oncogene Int-4 homolog, Proto-oncogene Wnt-3, wingless type MMTV integration site family member 3, Wnt 3 proto oncogene protein, WNT 3 proto oncogene protein precursor, wnt3, WNT3_HUMAN |
Backgroud |
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region. |
Swiss Prot |
P56703 |
Gene ID |
7473 |
Subcellular Localization |
Secreted extracellular matrix extracellular space |
Host |
Mouse |
Clone Type |
Monoclonal Antibody |
Subtype |
lgG1 |
Clone Number |
4F11-H1-F4 |
Protein MW |
40kDa |
Dilution Ratio |
WB 1:500-1000. |
Immunogen |
Recombinant protein of human Wnt3 |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: PBS with 0.02% sodium azide, 0.5% BSA, 50% glycerol, pH7.3. |
Storage |
Store at -20℃. Avoid freeze / thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Transfected |
Application |
WB |
Specification |
50ul 100ul |