Anti-PCBP2 Polyclonal Antibody_Others_Primary Antibodies_Antibodies_Solarbio-Global Leader in Antibody and Elisa Kit

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Chemical Synthesis

SKU	Tongzhou Beijing	Haidian Beijing	Wuhan	Guangzhou
K000367P-100ul	Inquiry	Inquiry	Inquiry	Inquiry
K000367P-50ul	Inquiry	Inquiry	Inquiry	Inquiry

English Name	Anti-PCBP2 Polyclonal Antibody
Chinese Name	异构核糖核蛋白E2抗体
Target	PCBP2
Synonym	Alpha CP2, Alpha-CP2, alphaCP-2, Cbp, CTBP, Heterogeneous nuclear ribonucleoprotein E2, Heterogenous nuclear ribonucleoprotein E2, hnRNP E2, hnRNP-E2, HNRNPE2, Hnrnpx, HNRPE2, Hnrpx, MGC110998, PCBP2, PCBP2_HUMAN, poly(rC) binding protein 2, Poly(rC)-binding protein 2, Putative heterogeneous nuclear ribonucleoprotein X, rCbinding protein 2
Backgroud	The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene.
Swiss Prot	Q15366
Gene ID	5094
Subcellular Localization	Cytoplasm Nucleus
Host	Rabbit
Clone Type	Polyclonal Antibody
Subtype	IgG
Protein MW	39kDa
Dilution Ratio	WB 1:500-1000.IHC 1:50-200.IF 1:50-200.
Immunogen	A synthetic peptide of human PCBP2
Public Immunogen Range	150-250aa
Purification Method	Affinity purification
Storage Buffer	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage	Store at -20℃, avoid freeze/thaw cycles.
Unit	Piece
Cross-Reactivity	Human Rat Mouse
Application	WB IHC IF
Specification	50ul 100ul