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My CartReactivity：Mouse,Rat,Human
Application：WB,IF,IHC
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze/thaw cycles.
Gene ID：23621
Host：Rabbit
Qty：
Size：
| Name | Anti-BACE1 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | WB 1:100-500. IHC 1:50-200. IF 1:50-200 |
| Target | BACE1 |
| Background | This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. |
| Swiss Prot | P56817 |
| Gene ID | 23621 |
| Subcellular Location | Cell surface Cytoplasmic vesicle membrane Endoplasmic reticulum Endosome Golgi apparatus Membrane Single-pass type I membrane protein trans-Golgi network |
| Immunogen | Recombinant protein of human BACE1 |
| Public Immunogen Range | 22-322aa |
| Calculated MW | 56kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide，50% glycerol，pH7.3. |
| Storage | Store at -20℃. Avoid freeze/thaw cycles. |
| Unit | Piece |
| Specification | 50ul 100ul |
| Reactivity | Mouse Rat Human |
| Application | WB IHC IF |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Western blot analysis with BACE1 antibody diluted at 1:500;Lane: SH-SY5Y.
Immunofluorescence analysis of SH-SY5Y cells using BACE1 antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Mouse hippocampus with BACE1 antibody diluted at 1:100.
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