Anti-ABL1 Polyclonal Antibody_Others_Primary Antibodies_Antibodies_Solarbio-Global Leader in Antibody and Elisa Kit

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Chemical Synthesis

SKU	Tongzhou Beijing	Haidian Beijing	Wuhan	Guangzhou
K001657P-100ul	Inquiry	Inquiry	Inquiry	Inquiry
K001657P-50ul	Inquiry	Inquiry	Inquiry	Inquiry

English Name	Anti-ABL1 Polyclonal Antibody
Chinese Name	磷酸化非受体酪氨酸激酶c-Abl抗体
Target	ABL1
Synonym	Abelson murine leukemia viral oncogene homolog 1,Abelson tyrosine protein kinase 1,Abl 1,ABL,ABL proto oncogene 1 non receptor tyrosine kinase,ABL1,ABL1_HUMAN,bcr/abl,bcr/c abl oncogene protein,c ABL,c abl oncogene 1 non receptor tyrosine kinase,c abl oncogene 1 receptor tyrosine kinase,c ABL1,JTK7,p150,Proto oncogene tyrosine protein kinase ABL1,Proto-oncogene c-Abl
Backgroud	This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons.
Swiss Prot	P00519
Gene ID	25
Subcellular Localization	Cytoplasm Lipid-anchor Mitochondrion Nucleus Nucleus membrane cytoskeleton
Host	Rabbit
Clone Type	Polyclonal Antibody
Subtype	IgG
Protein MW	123kDa
Dilution Ratio	WB 1:100-500. IHC 1:50-200. IF 1:50-200.
Immunogen	Recombinant protein of human ABL1
Public Immunogen Range	1000-1130aa
Purification Method	Affinity purification
Storage Buffer	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage	Store at -20℃, avoid freeze/thaw cycles.
Unit	Piece
Cross-Reactivity	Human Rat Mouse
Application	WB IHC IF
Specification	50ul 100ul