Anti-ARRB1 Polyclonal Antibody_Others_Primary Antibodies_Antibodies_Solarbio-Global Leader in Antibody and Elisa Kit

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SKU	Tongzhou Beijing	Haidian Beijing	Wuhan	Guangzhou
K001800P-100ul	Inquiry	Inquiry	Inquiry	Inquiry
K001800P-50ul	Inquiry	Inquiry	Inquiry	Inquiry

English Name	Anti-ARRB1 Polyclonal Antibody
Chinese Name	抑制素,β1抗体
Target	ARRB1
Synonym	ARB1, ARR1, ARRB1, ARRB1_HUMAN, Arrestin 2, Arrestin beta 1, Arrestin beta-1, Beta-arrestin-1
Backgroud	Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.
Swiss Prot	P49407
Gene ID	408
Subcellular Localization	Cell membrane Cell projection Cytoplasm Cytoplasmic vesicle Membrane Nucleus clathrin-coated pit pseudopodium
Host	Rabbit
Clone Type	Polyclonal Antibody
Subtype	IgG
Protein MW	47kDa
Dilution Ratio	WB 1:500-1000. IHC 1:50-200. IF 1:50-200. IP 1:500-1000.
Immunogen	Recombinant protein of human ARRB1
Public Immunogen Range	169-418aa
Purification Method	Affinity purification
Storage Buffer	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage	Store at -20℃, avoid freeze/thaw cycles.
Unit	Piece
Cross-Reactivity	Human Rat Mouse
Application	WB IHC IF IP
Specification	50ul 100ul